ECDC GUIDANCE Use of interferon-gamma release assays in support of TB diagnosis

ECDC GUIDANCE Use of interferon-gamma release assays in support of TB diagnosis

مروری بر روش‌های تشخیص ایمونولوژیک عفونت سل

Tuberculosis (TB) is a leading cause of mortality and morbidity in the world and this infection is a major public health challenge. TB control is largely dependent on the early diagnosis and managements of suspected cases. Today, for laboratory diagnosis of TB infection, several bacteriological and immunological methods such as sputum smear microscopy, sputum culture and tuberculin skin test ar...

Phenotyping chronic pulmonary aspergillosis by cluster analysis.

References 1 Pai M, Denkinger CM, Kik SV, et al. Gamma interferon release assays for detection of Mycobacterium tuberculosis infection. Clin Microbiol Rev 2014; 27: 3–20. 2 Diel R, Goletti D, Ferrara G, et al. Interferon-γ release assays for the diagnosis of latent Mycobacterium tuberculosis infection: a systematic review and meta-analysis. Eur Respir J 2011; 37: 88–99. 3 Sester M, van Leth F, ...

[combined Use of Interferon-gamma Release Assay and Low-dose Computed Tomography for Tuberculosis Screening Program of Health Care Workers].

OBJECTIVE To evaluate the value of the interferon-gamma release assays and low-dose computed tomography for the pulmonary tuberculosis screenings program of health care workers. DESIGN For the pulmonary tuberculosis (TB) screenings program, T-SPOT.TB (one of interferon-gamma release assays: IGRA) were performed on 332 health care workers (HCWs) with normal chest roentgenogram and without the ...

Can Interferon-Gamma Release Assays be helpful for the diagnosis of pulmonary and extrapulmonary tuberculosis?

The diagnosis of pulmonary tuberculosis and tuberculous pleurisy standard methods is difficult and slow. Now, high hopes to cells of T cells secreting interferon-gamma in response to antigens of Mycobacterium tuberculosis. Use of the immune response to TB diagnosis. A systematic review was performed of latest publications. Interferon-γ release assays (IGRA) on peripheral blood mononuclear cells...